‘crocidolite’

Asbestos

Saturday, March 13th, 2010

Malignant MesotheliomaAsbestos is classified into 2 groups based on its physical properties: the serpentines, which tend to be wavy and long, and the amphiboles, which are straight and rodlike. The most important member of the serpentines is chrysotile, which makes up more than 90% of the asbestos used in the United States. The amphibole group includes crocidolite, amosite, and tremolite, which is often found as a contaminant of chrysotile ore.

The use of asbestos can be traced through history as far back as the Stone Age, when it was mixed in with earthenware pots for strength. Though the versatility of asbestos has been known since ancient times, its use did not become widespread until the Industrial Revolution in the late 19th century, when mass quantities were needed for booming textile and insulation factories. Asbestos production increased during the next century until its peak in the 1970s. Despite the well-documented health risks from exposure, asbestos remains widely used, particularly in developing countries.

Three major diseases are associated with asbestos exposure: asbestosis, lung cancer and mesothelioma. Pleural plaques are the most common manifestation of exposure. This article focuses on asbestosis, which specifically refers to the bilateral diffuse interstitial fibrosis of the lungs caused by inhalation of asbestos fibers. (more…)

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What Is Pathophysiology?

Monday, March 1st, 2010

Understanding MesotheliomaThe 2 subgroups of asbestos are termed amphiboles and serpentines. Amphiboles are continued aciculate fibers with aerial length-to-diameter ratios and are aggressive to dissolution. These fibers abide in the tissues for years. Crocidolite is the amphibole best accessible commercially and is acerb associated with mesothelioma.

Serpentines accept a braid actualization and are added soluble. Chrysotile, the abandoned serpentine, accounts for 80-90% of bartering asbestos acclimated in the United States and Canada. Chrysotile is beneath baneful than crocidolite because of its abate length-to-diameter ratio, added tissue solubility, and addiction to drop in the axial airways. Chrysotile that has been attenuated with tremolite (a noncommercial amphibole) has been appropriate as the alone anatomic account of mesothelioma, although this is not accustomed universally. The apparatus by which asbestos fibers account mesothelioma is not able-bodied understood. One accessible account is that cancerous transformation of beef follows a foreign-body acknowledgment that is acquired by the baffling fibers. (more…)

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What is Asbestos?

Tuesday, February 16th, 2010

Asbestos
Asbestos is a mineral that occurs naturally in the environment and is typically divided into two mineralogical groups, but not all varieties have commercial use.

The family of amphibolites include crocidolite (also known as “blue asbestos”), the amosite (known as “brown asbestos), tremolite, anthophyllite and actinolite. Within the different types of amphibole fibers, only crocidolite and amosite are used commercially. However, the asbestos “noncommercial” (as tremolite, anthophyllite and actinolite) are also present as contaminants in commercial products include chrysotile asbestos, vermiculite and talc.

The other group of asbestos is the serpentine group that includes only the variety chrysotile asbestos. Despite its dangerous properties, chrysotile was immensely popular in the industry and represents 90% of the commercial use of asbestos in the United States.

Source: Pathology of Asbestos-related diseases (Victor L. Roggli et al. Eds., 2004).

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